A controlled clinical study on the efficacy of Khadira Churna Pratisarana with Madhu in management of Mukhapaka (Stomatitis) in Children

Mukhapaka in children is prevalent all over the world. It refers to an oral disease which occurs in two ways former one occures independently (Swantantrarogam) and latter occurs in association with (Anubandhirogam) other diseases like Grahani. It occurs due to Vit B12 deficiency, folate deficiency, leukemia, inflammatory bowel disease, stress, illness, dietary triggers. Nutritional deficiency etc. Mukhapaka is found in those with poor oral hygiene. In Mukhapaka Vata is moving through out the interior of mouth gives rise to ulcers which shift in different place of oral cavity. Dry makes lips coppery red. Tongue become intolerant to cold, feels heavy, cracked and feels as though full of thrones there is difficulty to open the mouth i.e. Mukhapaka. In present era, world is looking at Ayurveda with the hope that it is going to provide good asset to the treatment of ailing humanity. Sarvasaramukharogas are named as Mukhapaka, as it occurs by spreading completely in the Mukha. Mukharogas occurs due to intake of unwholesome food, curd, milk, fermented gruel, not cleaning the teeth daily, improper administration of inhalation, emesis, gargles and venesection etc

Discovery of Ranking Fraud for Mobile Apps

Ranking fraud within the mobile App market refers to deceitful or deceptive activities that have a purpose of bumping up the Apps within the quality list. Indeed, it becomes a lot of and a lot of frequent for App developers to use shady means that, like inflating their Apps’ sales or posting phony App ratings, to commit ranking fraud. Whereas the importance of preventing ranking fraud has been well known, there's restricted understanding and analysis during this space. to the current finish, during this paper, we offer a holistic read of ranking fraud and propose a ranking fraud detection system for mobile Apps. Specifically, we have a tendency to initial propose to accurately find the ranking fraud by mining the active periods, specifically leading sessions, of mobile Apps. Such leading sessions are often leveraged for sleuthing the native anomaly rather than international anomaly of App rankings. what is more, we have a tendency to investigate 3 kinds of evidences, i.e., ranking primarily based evidences, rating based evidences and review based evidences, by modeling Apps’ ranking, rating and review behaviors through applied math hypotheses tests

Study of hypoglycemic activity of Tinospora cordifolia in alloxan induced diabetic rabbits

Background: This study was designed to investigate the hypoglycemic effect of Tinospora Cordifolia in alloxan-induced diabetic rabbits.Methods: Rabbits were divided into four experimental groups: Non-diabetic rabbits treated with normal saline, Non-diabetic rabbits treated with TCREt, Diabetic rabbits treated with Metformin, Diabetic rabbits treated with TCREt. Treatment with drugs was started on the 8th day of alloxan treatment (i.e. day 1) and was continued for 30 days. Statistical evaluation was done using student’s ‘t’ test & one way ANOVA followed by Tuckey`s post hoc test. ‘p’ value less than 0.05 was considered statistically significant.Results: TCREt showed hypoglycemic action in alloxan induced diabetes rabbits. It did not produce hypoglycemia in non diabetic rabbits.Conclusion: Hypoglycemic action of TCREt is comparable to that of standard oral hypoglycemic drug metformin

Laser-based detection and depth estimation of dry and water-filled potholes: A geometric approach

In secondary Indian roads, one often encounters potholes which can be either dry or water-filled. Accordingly, to ensure safe driving, it is imperative to detect potholes and estimate their depths in either condition. In this paper, we develop a physics-based geometric framework, where such detection and depth-estimation can be accomplished using suitable laser. Specifically, we relate dry pothole depth to measured optical deviation using simple ray optics. Further, we use Snell's law of refraction to obtain a quartic equation, and its appropriate real root to relate water-filled pothole depth to the corresponding optical deviation. Here we take into account diminishing resolu- tion with increasing distance from the camera. We conclude by experimentally validating our method

Impact of educational session on knowledge and attitude towards antimicrobial prescribing and awareness about antimicrobial resistance among undergraduate medical, dental and nursing students: a comparative study

Background: Educational interventions targeting undergraduate medical students provide a great opportunity to strengthen the efforts to promote rational prescribing and to decrease antimicrobial resistance. A better understanding of knowledge and beliefs of students about issues of antimicrobial use and resistance, and analysing the improvement after educational session, can assist in devising an effectively tailored educational intervention. The objective of this study was to comparison of knowledge and attitude about antimicrobial prescribing and awareness about resistance amongst medical, dental and nursing undergraduates before and after an educational session on antimicrobial use and resistance.Methods: A pre-validated questionnaire on knowledge and attitude about antimicrobial use and resistance was distributed to second year medical (80), dental (61) and nursing (37) students before and after an educational session. Results obtained were compared within and between the groups by using paired t-test and one-way ANOVA respectively. P-value<0.05 was considered to be statistically significant.Results: All groups showed statistically significant improvement in knowledge and attitude scores following the session on antimicrobial use and resistance (P<0.001). Post-session attitude scores of medical students were better than that of dental and was statistically significant (P=0.006). The pre-session evaluation showed that medical students had better knowledge and attitude about antimicrobial use and resistance as compared to dental (P<0.001) and nursing students(P<0.001).Conclusions: Significant improvement in attitude and basic knowledge following an educational session about antimicrobial prescribing and awareness about antimicrobial resistance in undergraduate students suggest establishment of special course on rational prescription of antimicrobials in undergraduate curriculum

Prospective, non-randomized, parallel group, comparative observational study to compare maternal and neonatal outcome after regional and general anesthesia for Lower Segment Caesarean Section

Background: LSCS is a routine obstetric procedure performed under general anesthesia (GA) or regional anesthesia (RA). Choice of anesthesia depends on factors like gestational age, parity, co-morbidities, urgency of situation, etc. Both GA and RA involve the use of various medications which may influence maternal and neonatal outcome. As there are few studies comparing maternal and fetal outcome in RA and GA for LSCS in Indian population, the present study was taken up. Objectives of the study was to compare the maternal and neonatal outcome after RA and GA for LSCS.Methods: 60 subjects with indications for LSCS were assigned non-randomly into two groups, 30 for GA and 30 for RA, at the discretion of anesthesiologist. The demographic, anthropometric and clinical data was recorded for all subjects. The maternal outcome after RA and GA for LSCS was assessed by parameters like maternal blood loss, postoperative pain, postoperative nausea and vomiting, maternal satisfaction and neonatal outcome by parameters like birth weight, APGAR scores and NICU admissions. The maternal and neonatal outcome between the two groups was compared.Results: All subjects had clear indications for CS. In most of the subjects it was undertaken as an emergency procedure. GA was preferred in high risk subjects. Maternal blood loss, postoperative pain, NICU admissions, need for resuscitation was less under RA compared to GA. There was no difference in PONV, maternal satisfaction, birth weight and need for intubation.Conclusions: LSCS under RA showed a more favourable maternal and neonatal outcome

Influence of Aggregate Size on Soil Moisture Retention

Soil aggregates ranging from 0.5 to 9.5 mm. in diameter from Nicollet silt loam were used to study the effect of aggregate size on soil moisture retention. It was concluded that (a) between suctions of 0.10 and 1.0 bar, the gravimetric percent moisture retained by various sized aggregates was in the following order: 0.5 \u3c 1.0 \u3c 2.0 ≤ 3.0 ≤ 5.0 ≤ 9.5 mm.; (b) between suctions of 1.0 and 5.0 bars, the gravimetric percent moisture retained was in the following order: 0.5 \u3c 1.0 ≤ 2.0 ≤ 3.0 ≤ 5.0 ≤ 9.5 mm.; and (c) at suction of 10 and 15 bars, the moisture retained by aggregates of various sizes was essentially the same

Synthesis and preliminary biological profile of new NO-donor tolbutamide analogues.

We describe a new class of NO-donor hypoglycemic products obtained by joining tolbutamide, a typical hypoglycemic sulfonylurea, with a NO-donor moiety through a hard link. As NO-donors we chose either furoxan (1,2,5-oxadiazole 2-oxide) derivatives or the classical nitrooxy function. A preliminary biological characterization of these compounds, including stimulation of insulin release from cultured rat pancreatic β-cells and in vitro vasodilator and anti-aggregatory activities, is reported